Isotopically Labeled Compounds
![Medchemexpress LLC Phen-2,3,5,6-d4-ol-d, 4,4'-[1-(methyl-d3)ethylidene-2,2,2-d3]bis- | 96210-87-6 | 99.95% | 244.38 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385928-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Phen-2,3,5,6-d4-ol-d, 4,4'-[1-(methyl-d3)ethylidene-2,2,2-d3]bis- | 96210-87-6 | 99.95% | 244.38 | 25 MG
Bisphenol A-d16 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductive disorders.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Nintedanib-d8 | 1624587-87-6 | 99.9% | C31H25D8N5O4 | 1 MG
Nintedanib-d8 is deuterium labeled Nintedanib, a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-glucose-13C,d-1 | 201417-06-3 | 99.7% | 182.15 | C5(13C)H11DO6 | 10 MG
D-Glucose-13C,d-1 is an isotopically labeled form of D-(+)-glucose used as a stable isotope tracer for metabolic and analytical studies. It is supplied as a powder with high isotopic and chemical purity for research applications.
- Single 13C label and one deuterium substitution (d-1).
- High chemical purity (99.7%).
- Molecular weight approximately 182.15 g/mol.
- Powder form with defined storage: powder -20°C (3 years) or 4°C (2 years).
- Available in small research pack sizes, including 10 mg.
Cambridge Isotope Laboratories TAUROCHENODEOXYCHOLIC ACID, SODIUM SALT (CP 97%) (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL, 1 ML
TAUROCHENODEOXYCHOLIC ACID, SODIUM SALT (CP 97%) (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL, 1 ML
Cambridge Isotope Laboratories METHYL IODIDE + COPPER WIRE (D1, 98%), 5 G, 992-96-1
METHYL IODIDE + COPPER WIRE (D1, 98%), 5 G, 992-96-1
Medchemexpress LLC D-Alanine-d7 | 2483831-62-3 | 99.0% | 96.14 | 1 MG
D-Alanine-d7 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Rofecoxib-d5 | 544684-93-7 | 319.39 | 500 UG
Rofecoxib-d5 is a deuterium-labeled variant of Rofecoxib, a potent and orally active COX-2 inhibitor. It exhibits high selectivity for COX-2 over human COX-1, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, respectively, and an over 1000-fold selectivity for COX-2 compared to human COX-1 in U937 cells and Chinese hamster ovary cells.
- Can be utilized as a tracer in various applications.
- Serves as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes like deuterium can influence the pharmacokinetic and metabolic profiles of compounds.
Medchemexpress LLC L-Glutamine-13C5,15N2,d5 | 2123439-02-9 | 158.13 | 5 MG
L-Glutamine-13C5, 15N2, d5 is the deuterium, 13C-, and 15N-labeled form of L-Glutamine. It is a non-essential amino acid involved in numerous metabolic processes, providing a source of carbons for oxidation in some cells. This product is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Posaconazole-d5 | 1217785-83-5 | 99.1% | 705.81 g/mol | C37H37D5F2N8O4 | 10 MG
Posaconazole-d5 is the deuterium-labeled analogue of posaconazole, provided as a high-purity stable isotope for use as an internal standard or tracer in analytical workflows. It is intended for quantitative method development and bioanalytical applications, supporting accurate quantitation in complex matrices when used with appropriate instrumentation and controls.
- High isotopic purity for reliable internal standard performance.
- Suitable for NMR, GC-MS, and LC-MS quantitative analysis.
- High chemical purity for reproducible analytical results.
- Available in small-mass vials convenient for trace-level experiments.
- Stable under recommended storage conditions to preserve integrity.
Cambridge Isotope Laboratories BUSULFAN (TETRAMETHYLENE-D8, 98%), 0.1 G, 116653-28-2
BUSULFAN (TETRAMETHYLENE-D8, 98%), 0.1 G, 116653-28-2
Medchemexpress LLC 4-hydroxybenzonitrile-d4 | 1025089-21-7 | MFCD08704964 | 123.15 | C7HD4NO | 5mg
4-Cyanophenol-d4 is the deuterium labeled 4-Cyanophenol[1]
Medchemexpress LLC Dodecanoic-12,12,12-d3 acid | 79050-22-9 | MFCD00190437 | 98.9% | 203.34 | C12H21D3O2 | 100mg
Lauric acid-d33 is the deuterium labeled Lauric acid Lauric acid is a middle chain-free fatty acid with strong bactericidal properties The EC50s for P acnes S aureus S epidermidis are 2 6 4 g/mL respectively
Medchemexpress LLC 4-n-octyl-anisole-d17 | 1219794-56-5 | 99.2% | 237.46 | C15H7D17O | 10 MG
4-n-Octyl-anisole-d17 is the deuterium-labeled analogue of 4-n-octyl-anisole intended for research use as a tracer and internal standard in quantitative analytical methods. It is used in pharmacokinetic and metabolic studies and is compatible with NMR, GC-MS, and LC-MS workflows.
- Deuterium labeling (d17) provides a clear mass shift for tracer and internal standard applications.
- Compatible with NMR, GC-MS, and LC-MS for quantitative analysis.
- Stable isotope labeling supports pharmacokinetic and metabolic profiling.
- Chemical formula C15H7D17O and molecular weight 237.46 aid molecular identification.
- High reported purity (99.2%) suitable for analytical standards.
- Available in small research package sizes (1 mg, 5 mg, 10 mg).
Medchemexpress LLC Telmisartan-d3 | 1189889-44-8 | >99.7% | 517.64 | 1 MG
Telmisartan-d3 is a deuterium-labeled version of Telmisartan, a potent and long-lasting antagonist of the angiotensin II type 1 receptor (AT1). It selectively inhibits the binding of 125I-AngII to AT1 receptors with an IC50 of 9.2 nM.
- Intended for research use only
- Can be utilized as a tracer or internal standard
- Suitable for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS
- Deuteration influences pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Bis-Tris-d19 | 352534-93-1 | 99% | 50 MG
Bis-Tris-d19 is the deuterium-labeled form of Bis-Tris, a commonly used buffer. Deuteration, which involves incorporating stable heavy isotopes into drug molecules, is used as tracers for quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs. This compound is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.