Antibody-Binding Proteins and Conjugates
Biotium Cytokeratin 8(K8/383), CF647 conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant)
Cayman Chemical AloglIptInbenzoate salt 50mg
An orally bioavailable DPP-4 inhibitor (IC50 = 6.9 nM) that is selective for DPP-4 over DPP-2, DPP-8, DPP-9, prolyl endopeptidase, FAP, and tryptase (IC50s = >100,000 nM); inhibits DPP-4 activity in vivo in rats, dogs, and cynomolgus monkeys (EC50s = 3.4, 4.9, and 5.6 ng/ml, respectively, in plasma); increases plasma GLP-1 and insulin levels and decreases blood glucose levels during an oral glucose challenge in Zucker fa/fa rats (10 mg/kg); decreases plasma DPP-4 activity and increases GLP-1 levels in diabetic ob/ob mice when administered for 29 days (2.8 mg/kg per day)
Jackson Immuno Research Labs Peroxidase-ChromPure Rat Transferrin
Peroxidase-ChromPure Rat Transferrin
Jackson Immuno Research Labs Peroxidase-ChromPure Mouse IgG Fab fragment
Peroxidase-ChromPure Mouse IgG Fab fragment
Jackson Immuno Research Labs DyLight 405-ChromPure Bovine IgG whole molecule
DyLight 405-ChromPure Bovine IgG whole molecule
Jackson Immuno Research Labs Cy3-ChromPure Mouse IgG Fab fragment
Cy3-ChromPure Mouse IgG Fab fragment
Abcam 143Nd Metal Conjugation Kit - Lightning-Link, 10UG
Labeling in < 4 hrs with 30 secs hands-on time using 143Nd Metal Conjugation Kit - Lightning-Link ab269828. 100% antibody recovery.
The product is subject to the following: Abcam Restricted Use Statement
Biotium Fibronectin(HFN7.1), Biotin conjugate, 0.1mg/mL
Fibronectin is a dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. This MAb is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. It blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific ba
Jackson Immuno Research Labs Cy3-ChromPure Chicken IgY (IgG) whole molecule
Cy3-ChromPure Chicken IgY (IgG) whole molecule
Bioworld Nanogold*- rabbit (NRI) AB, 0.5 mL
Nanogold* shines when it comes to EM. It is the new gold standard. Nanogold* reagents diffuse easily tens of microns into tissues and into permeabilized cells and cell nuclei, to where most colloidal gold probes have difficulty in reaching.Smallest commer
Biotium CD8b, Mouse(H35-17.2), CF594 conjugate, 0.1mg/mL
This rat monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Cayman Chemical MonsInsodIum salt 500mg
An ionophorous antibiotic that preferentially forms complexes with monovalent cations for lipid-soluble transport across membrane bilayers; active against Gram-positive bacteria such as Micrococcus, Bacillus, and Staphylococcus (MICs = 1-12.5 UG/ml), of P. falciparum and Coccicdium protozoa, and certain viruses
Cayman Chemical on-AE3-208sodIum salt 50mg
An antagonist of the EP4 receptor (Ki = 1.3 nM) that less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors; implicates EP4 signaling in immune and autoimmune responses, inflammation, and cancer
Abcam Oligonucleotide Conjugation Kit, 3 x 100UG
Abcam's Oligonucleotide Conjugation Kit (ab218260) offers several standout features: - Rapid Conjugation: enables generation of antibody-oligonucleotide conjugates in less than 2 hours. - High Efficiency: achieves high levels of antibody and oligonucleotide recovery, with conjugation efficiency ~ 95-100%. - Versatility: Suitable for conjugating antibodies to single-stranded oligonucleotides (10-120 bases) and double-stranded oligonucleotides (up to 80 bases), providing flexibility for various research needs
The product is subject to the following: Abcam Restricted Use Statement