Cayman Chemical 11dehydro Thromboxn B2 ELI 96
An immunomodulatory agent selectively inhibits IL-12-induced tyrosine phosphorylation of TYK2 and STAT3 over JAK2 in primary mouse concanavalin A-activated T cells at 10 UM does not inhibit EGFR (IC50 1250 UM) unlike most tyrphostins and has commonly been used as an inactive control for tyrphostin tyrosine kinase inhibitory activity inhibits CD40L-induced IL-12 production and NF-KB translocation in primary mouse macrophages reduces the development and severity of EAE in mice inhibits GABA-induced activation of wild-type GABAA receptors and GABAAY365F/Y367F receptors expressed in Xenopus oocytes at 200 UM