Native Proteins and Derivatives
Biotium MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1)(2F6), CF647 conjugate, 0.1mg/mL
Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli, including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4 and ASK 1 (MEK kinase- 5). MEK kinase-1 activates the ERK and c-Jun NH2-terminal kinase (JNK) pathways by phosphorylation of MAP2K1 and MAP2K4, and also activates the central protein kinases of the NFB pathway, CHUK and IKBKB. Additionally, MEK kinase-1 uses an E3 ligase through its PHD domain, a RING-finger-like structure, to target proteins for degradation through ubiquitination.
Biolegend Ultra-LEAFTM Purified anti-hum
Ultra-LEAF™ Purified anti-human PLAUR (uPAR) [A20095H]; Isotype: Mouse IgM, κ; Reactivity: Human; Apps: Block; Size: 100 μg
Biolegend HRP anti-Neurofilament H NF-H
HRP anti-Neurofilament H (NF-H), Nonphosphorylated [SMI 32]; Isotype: Mouse IgG1; Reactivity: Human, Mouse, Rat; Apps: IHC-P, WB; Size: 100 μg
Biolegend Alexa FluorR 647 anti-HMOX1
Alexa Fluor 647 anti-HMOX1 [W19398C]; Isotype: Rat IgG2a, κ; Reactivity: Human; Apps: ICFC, ICC; Size: 100 μg
Biolegend Purified anti-mouse Panendothe
Purified anti-mouse Panendothelial Cell Antigen [MECA-32]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC, ICC, IHC-F, IP, WB; Size: 500 μg
CPC Scientific H-Lys-Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH (trifluoroacetate salt) 1MG
ONE-LETTER SEQUENCE: KEAKSQGGSNMOLECULAR FORMULA: C39H68N14O17MOLECULAR WEIGHT:1005.05STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [318950-01-5], SYNONYMS: Lys-STFRESEARCH AREA: Immunomodulation
Abcam Recombinant Human 15-PGDH protein
Recombinant Human 15-PGDH protein
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical ChymostatIn 10mg
A potent inhibitor of chymotrypsin and chymase (Ki = 9.36 and 13.1 nM, respectively), that less effectively blocks the activity of cathepsins, papain, and leukocyte elastase