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Anti-Myeloperoxidase Polyclonal Primary Antibody is intended for laboratory use in the detection of the myeloperoxidase protein in formalin-fixed, paraffin-embedded human tissue stained in qualitative immunohistochemistry (IHC) on BenchMark IHC/ISH instruments. This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls. This antibody is intended for in vitro diagnostic (IVD) use.
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The epitope of this antibody is located in the 8th type III repeat in the cell-binding region of fibronectin Fibronectins are disulfide-linked dimeric glycoproteins of approximately 440 kDa They possess at least four binding sites for collagen glycosaminoglycans transglutaminase and a cell surface receptor Fibronectins are involved in cell adhesion tissue organization and wound healing Fibronectins are present in basement membranes interstitial connective tissue matrix and blood Cellular fibronectin is widely distributed in the stroma of many malignant tumors This MAb is excellent for staining of formalin-fixed paraffin-embedded tissues
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The epitope of this antibody is located in the 8th type III repeat in the cell-binding region of fibronectin Fibronectins are disulfide-linked dimeric glycoproteins of approximately 440 kDa They possess at least four binding sites for collagen glycosaminoglycans transglutaminase and a cell surface receptor Fibronectins are involved in cell adhesion tissue organization and wound healing Fibronectins are present in basement membranes interstitial connective tissue matrix and blood Cellular fibronectin is widely distributed in the stroma of many malignant tumors This MAb is excellent for staining of formalin-fixed paraffin-embedded tissues
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
In Western blotting this antibody recognizes proteins in MW range of 265-400 kDa identified as different glycoforms of EMA EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack In immunohistochemical assays it superbly stains routine formalin/paraffin carcinomas Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
In Western blotting this antibody recognizes proteins in MW range of 265-400 kDa identified as different glycoforms of EMA EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack In immunohistochemical assays it superbly stains routine formalin/paraffin carcinomas Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
In Western blotting this antibody recognizes proteins in MW range of 265-400 kDa identified as different glycoforms of EMA This MAb reacts with the DTRP epitope in the tandem repeats Thealpha subunit has cell adhesive properties It can act both as an adhesion and an anti-adhesion protein EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack The beta subunit contains a C-terminal domain which is involved in cell signaling through phosphorylations and protein-protein interactions In immunohistochemical assays it superbly stains routine formalin/paraffin carcinoma tissues Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
In Western blotting this antibody recognizes proteins in MW range of 265-400 kDa identified as different glycoforms of EMA This MAb reacts with the DTRP epitope in the tandem repeats Thealpha subunit has cell adhesive properties It can act both as an adhesion and an anti-adhesion protein EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack The beta subunit contains a C-terminal domain which is involved in cell signaling through phosphorylations and protein-protein interactions In immunohistochemical assays it superbly stains routine formalin/paraffin carcinoma tissues Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More