Didesmethyl cariprazine is the predominant circulating, orally active metabolite of cariprazine used in pharmacology research to probe dopaminergic and serotonergic mechanisms. It crosses the blood-brain barrier and modulates dopamine and serotonin receptors, making it useful for receptor profiling, metabolism studies, and in vivo pharmacokinetic investigations.
- Orally active, blood-brain barrier permeable compound.
- Partial agonist at D2 and D3 receptors.
- Full agonist at 5-HT1A and antagonist at 5-HT2B.
- Suitable for in vitro receptor pharmacology studies.
- Applicable to in vivo pharmacokinetic and metabolism research.
- Provided as a solid with high reported purity for research use.