CAS RN 301836-41-9
CAS RN 301836-41-9
IUPAC Name:
4-[4-(2H-1,3-benzodioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide
Synonyms:
4-[4-(2H-1,3-benzodioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide
Molecular Weight (g/mol):
384.4
Molecular Formula:
C22H16N4O3
InChi Key:
FHYUGAJXYORMHI-UHFFFAOYSA-N
SMILES:
NC(=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=CC=N1)C1=CC2=C(OCO2)C=C1
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MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor VI, SB431542
TGF-β RI Kinase Inhibitor VI, SB431542, CAS 301836-41-9, is a cell-permeable inhibitor of SMAD2 phosphorylation. Inhibits the activity of ALK4 and ALK5 (IC50 = 140 nM and 94 nM, respectively).
2
MilliporeSigma™ Calbiochem™ InSolution™ TGF-β RI Kinase Inhibitor VI, SB431542
The InSolution™ TGF-β RI Kinase Inhibitor VI, SB431542 controls the biological activity of TGF-β RI. Primarily used for Phosphorylation & Dephosphorylation applications.
3
Tocris Bioscience™ SB 431542
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7