Immunohistochemistry Reagents

Thermo Scientific™ Pierce™ LDH Cytotoxicity Assay Kit

Quantitatively measure lactose dehydrogenase released into the media from damaged cells as a biomarker for cellular cytotoxicity and cytolysis using a colorimetric assay.

Thermo Scientific™ Pierce™ Immunostain Enhancer

Increase signal intensity 3- to 12-fold and antibody dilution 5- to 20-fold beyond normal using both chromogenic or fluorescent IHC substrates.

Thermo Scientific™ Pierce™ Peroxidase Suppressor

Stable, easy-to-use endogenous peroxidase inhibitor to reduce background signal from cells and tissues in HRP-based IHC staining.

Thermo Scientific™ Pierce™ Hoechst 3342 Fluorescent Stain

High-quality Hoechst dye solution for fluorescent staining of DNA and nuclei in fixed- or live-cell imaging techniques.

Thermo Scientific™ Pierce™ Peroxidase IHC Detection Kit

Bundles the Pierce Metal Enhanced DAB Substrate Kit with all components to stain, counterstain and preserve results from frozen or paraffin tissue sections.

Thermo Scientific™ Pierce™ Protein Transfection Reagent

Form complexes with proteins, peptides, antibodies and other biologically active molecules for direct intracellular delivery using this cationic lipid mixture.

Thermo Scientific™ Pierce™ Methanol-free Formaldehyde Ampules

Vials of high-quality, methanol-free formaldehyde, a general IHC fixative and reversible amine-crosslinking agent for protein and nucleic acid samples.

Thermo Scientific™ Pierce™ DAPI Nuclear Counterstain

Highly pure diamidino-2-phenylindole (DAPI) dye for fluorescent staining of DNA content and nuclei in fixed-cell imaging techniques.

Thermo Scientific™ Pierce™ beta-Galactosidase Precipitating Substrates

Detect beta-galactosidase expression from vectors, plasmids, or DNA fragments with this chromogenic substrate.

Thermo Scientific™ Pierce™ Metal Enhanced DAB Substrate Kit

Special formulation of diaminobenzidine peroxidase substrate that uses cobalt and nickel chloride to yield intense color for IHC staining.

Thermo Scientific™ Pierce™ ABC Staining Kits

Detect biotinylated secondary antibodies by IHC using the highly sensitive avidin-biotin complex (ABC) technique.

BD Horizon™ BV480 Rat Anti-Mouse CD117

Widespread expression of CD117 in hematopoietic precursors is consistent with participation of c-Kit and its ligand in regulation of several hematopoietic lineages. BD Horizon™ BV480 Rat Anti-Mouse CD117 is also involved in the regulation of some events during the development of T lymphocytes. CD117 is also expressed by mast cells and by dendritic cells found in the periarteriolar lymphocytoc sheaths (T-cell areas) of splenic white pulp.

BD Horizon™ BV480 Mouse Anti-NHP CD45

D058-1283 is a CD45 monoclonal antibody specific for non-human primate leucocytes. BD Horizon™ BV480 Mouse Anti-NHP CD45 antibody reacts with baboon, Rhesus and Cynomolgus Macaque leucocytes in a similar pattern to CD45 binding to leukocyte common antigen (LCA) on human cells.  

BD Horizon™ BV480 Rat Anti-Mouse CD90.2

CD90 is a glycophosphatidylinositol-anchored membrane glycoprotein of Ig superfamily that is involved in signal transduction. BD Horizon™ BV480 Rat Anti-Mouse CD90 mediates adhesion of thymocytes to thymic stroma. The 53-2.1 antibody has been reported to block the binding of the Rat Anti-Mouse CD90.2 antibody (Clone 30-H12) to immobilized thymocyte membranes.

BD Horizon™ BV480 Mouse Anti-Human IgM

IgM is an important component in the first line of defense against foreign pathogens, but may also play a role in autoimmune diseases. BD Horizon™ BV480 Mouse Anti-Human IgM monomers consist of two light and two heavy chains. Unlike the heavy chain of an IgG antibody which contains 3 constant Ig domains, the μ heavy chain of IgM contains 4 constant Ig domains.

BD Horizon™ BV480 Mouse Anti-Human TCR γδ

The γδ TCR is associated with the signal-transducing CD3 complex. BD Horizon™ BV480 Mouse Anti-Human TCR γδ is expressed by thymocytes and by peripheral T cell subsets (γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors.

BD Horizon™ BV480 Mouse Anti-Human CD1a

CD1a is expressed on cortical thymocytes, dendritic cells and Langerhans cells. BD Horizon™ BV480 Mouse Anti-Human CD1a has structural similarities to the MHC class I antigen, and plays a role in antigen presentation. 

BD Horizon™ BV480 Mouse Anti-Human CD20

CD20 is expressed on pre-B-cells, resting and activated B cells, and follicular dendritic cells, but not plasma cells. BD Horizon™ BV480 Mouse Anti-Human CD20 is observed in low levels on a small subset of normal circulating T lymphocytes. The CD20 molecule is involved in the regulation of B-cell activation.

BD Horizon™ BV480 Mouse Anti-Rat CD90/Mouse CD90.1

CD90 (Thy-1) is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. BD Horizon™ BV480 Mouse Anti-Rat CD90/Mouse CD90.1 also mediates adhesion of mouse thymocytes to mouse thymic stroma. The OX-7 clone has also been reported to crossreact with rabbit and guinea pig thymus, brain, and intestine.

Phalloidin DyLight 680, Invitrogen™

Phalloidin Control, DyLight 680 conjugate, 21839, from Invitrogen™., 21839, from Invitrogen™. Species Reactivity: Many; Applications: ICC, IF, IHC.

BD Horizon™ BV480 Mouse Anti-Mouse CD45.2

The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction. BD horizon™ BV480 Mouse Anti-Mouse CD45.2 has 104 monoclonal antibody that recognizes the CD45 (Leukocyte Common Antigen) present on all leucocytes of most mouse strains.

BD Horizon™ BV480 Mouse Anti-Human CD4

CD4 distribution on lymphocytes is similar for both human and monkey cells. BD Horizon™ BV480 Mouse Anti-Human CD4,  with the majority of CD4-positive lymphocytes being CD8-negative and lacking reactivity with antibodies to B- or NK-cell markers.

BD Horizon™ BV480 Mouse Anti-Human CD4

CD4 is expressed on T-helper/inducer lymphocytes and monocytes. BD Horizon™ BV480 Mouse Anti-Human CD4 serves as a T cell coreceptor for MHC class II antigen recognition and as a receptor for the human immunodeficiency virus (HIV). The SK3 antibody inhibits HIV binding to CD4+ cells.

BD Horizon™ BV480 Mouse Anti-Human CD64

CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. BD Horizon™ BV480 Mouse Anti-Human CD64 associates with a signaling FcRγ homodimer to form the functional high affinity FcγRI complex and functions in both innate and adaptive immune responses.

BD Horizon™ BV480 Mouse Anti-Human CD123

IL-3Rα is expressed on a subset of peripheral blood dendritic cells, myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. BD Horizon™ BV480 Mouse Anti-Human CD123 is the 70 kDa IL-3 receptor α chain (IL-3Rα) that associates with the 120-140 kDa β subunit (CD131/Common β-chain/βc) to form the functional IL-3 receptor complex.

BD Horizon™ BV480 Mouse Anti-Human CD38

CD38 is expressed by other cells including monocytes, macrophages, dendritic cells, NK cells, myeloid and erythroid precursors and some epithelial cells. BD Horizon™ BV480 Mouse Anti-Human CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose.

BD Horizon™ BV480 Rat Anti-Mouse CD45

BD Horizon - BV480 Rat Anti-Mouse CD45 - CD45 is a transmembrane glycoprotein which is expressed at high levels on cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific.

BD Horizon™ BV480 Rat Anti-Mouse CD11b

CD11b serves as the alpha chain of the heterodimeric Mac-1 integrin (CD11b/CD18, αMβ2), also known as complement receptor 3 (CR3). BD Horizon™ BV480 Rat Anti-Mouse CD11b is a 170-kDa type 1 transmembrane glycoprotein and belongs to the Integrin alpha chain family.

BD Horizon™ BV480 Mouse Anti-Human CD3

CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. BD Horizon™ BV480 Mouse Anti-Human CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε

BD Horizon™ BV480 Rat Anti-Mouse IgD

The 11-26c.2a monoclonal antibody specifically binds to mouse immunoglobulin D of all Igh-C haplotypes and it does not react with other immunoglobulin isotypes. BD Horizon™ BV480 Rat Anti-Mouse IgD is expressed on the splenic B-cell surface with high affinity, it does not induce proliferation of splenic B cells in vitro.

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