Immunohistochemistry Reagents

Thermo Scientific™ Pierce™ LDH Cytotoxicity Assay Kit Available on GSA/VA Contract for Federal Government customers only.

Quantitatively measure lactose dehydrogenase released into the media from damaged cells as a biomarker for cellular cytotoxicity and cytolysis using a colorimetric assay.

Thermo Scientific™ Pierce™ DAPI Nuclear Counterstain Available on GSA/VA Contract for Federal Government customers only.

Highly pure diamidino-2-phenylindole (DAPI) dye for fluorescent staining of DNA content and nuclei in fixed-cell imaging techniques.

Thermo Scientific™ Pierce™ Immunostain Enhancer

Increase signal intensity 3- to 12-fold and antibody dilution 5- to 20-fold beyond normal using both chromogenic or fluorescent IHC substrates.

Thermo Scientific™ Pierce™ Peroxidase Suppressor

Stable, easy-to-use endogenous peroxidase inhibitor to reduce background signal from cells and tissues in HRP-based IHC staining.

Thermo Scientific™ Pierce™ Peroxidase IHC Detection Kit

Bundles the Pierce Metal Enhanced DAB Substrate Kit with all components to stain, counterstain and preserve results from frozen or paraffin tissue sections.

Thermo Scientific™ Pierce™ ABC Staining Kits Available on GSA/VA Contract for Federal Government customers only.

Detect biotinylated secondary antibodies by IHC using the highly sensitive avidin-biotin complex (ABC) technique.

Thermo Scientific™ Pierce™ Protein Transfection Reagent Available on GSA/VA Contract for Federal Government customers only.

Form complexes with proteins, peptides, antibodies and other biologically active molecules for direct intracellular delivery using this cationic lipid mixture.

Thermo Scientific™ Pierce™ Methanol-free Formaldehyde Ampules Available on GSA/VA Contract for Federal Government customers only.

Vials of high-quality, methanol-free formaldehyde, a general IHC fixative and reversible amine-crosslinking agent for protein and nucleic acid samples.

Thermo Scientific™ Pierce™ beta-Galactosidase Precipitating Substrates

Detect beta-galactosidase expression from vectors, plasmids, or DNA fragments with this chromogenic substrate.

Thermo Scientific™ Pierce™ Hoechst 3342 Fluorescent Stain Available on GSA/VA Contract for Federal Government customers only.

High-quality Hoechst dye solution for fluorescent staining of DNA and nuclei in fixed- or live-cell imaging techniques.

Thermo Scientific™ Pierce™ Metal Enhanced DAB Substrate Kit Available on GSA/VA Contract for Federal Government customers only.

Special formulation of diaminobenzidine peroxidase substrate that uses cobalt and nickel chloride to yield intense color for IHC staining.

BD Horizon™ BV480 Mouse Anti-Human TCR γδ

The γδ TCR is associated with the signal-transducing CD3 complex. BD Horizon™ BV480 Mouse Anti-Human TCR γδ is expressed by thymocytes and by peripheral T cell subsets (γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors.

BD Horizon™ BV480 Mouse Anti-Human CD27

With its ligand CD70, CD27 acts in a co-stimulatory fashion on T lymphocytes. BD Horizon™ BV480 Mouse Anti-Human CD27 is present on most peripheral blood T lymphocytes and medullary thymocytes and CD27 antigen is upregulated upon activation with the release of a soluble form, 28 to 32 kDa.

BD Horizon™ BV480 Mouse Anti-Mouse CD45.2

The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction. BD horizon™ BV480 Mouse Anti-Mouse CD45.2 has 104 monoclonal antibody that recognizes the CD45 (Leukocyte Common Antigen) present on all leucocytes of most mouse strains.

BD Horizon™ BV480 Mouse Anti-Human CD11c

CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells. BD Horizon™ BV480 Mouse Anti-Human CD11c associates with CD18 to form the CD11c/CD18 complex that binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1.

BD Horizon™ BV480 Mouse Anti-Human CD86

CD86 (B70/B7-2) is expressed primarily on monocytes, dendritic cells and activated B cells. BD Horizon™ BV480 Mouse Anti-Human CD86 is a ligand for CD28 and CTLA-4 and plays an important role in costimulation of T cells in primary immune response.

BD Horizon™ BV480 Mouse Anti-Human CD28

The CD28.2 monoclonal antibody specifically binds to CD28, a 44kDa homodimeric transmembrane glycoprotein present on most mature T cells, thymocytes and plasma cells. BD Horizon™ BV480 Mouse Anti-Human CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in T cell-B cell interactions.

BD Horizon™ BV480 Mouse Anti-Human CD20

CD20 is expressed on pre-B-cells, resting and activated B cells, and follicular dendritic cells, but not plasma cells. BD Horizon™ BV480 Mouse Anti-Human CD20 is observed in low levels on a small subset of normal circulating T lymphocytes. The CD20 molecule is involved in the regulation of B-cell activation.

BD Horizon™ BV480 Mouse Anti-Human CD138

CD138 is strongly expressed on multiple-myeloma-derived cell lines and malignant plasma cell populations. BD Horizon™ BV480 Mouse Anti-Human CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III, and V, tenascin, thrombospondin, and antithrombin III.

BD Horizon™ BV480 Mouse Anti-Human CD25

CD25 is expressed on regulatory T cells, activated lymphocytes (T and B), and monocytes. BD Horizon™ BV480 Mouse Anti-Human CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation.

BD Horizon™ BV480 Mouse Anti-Human CD62L

CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. BD Horizon™ BV480 Mouse Anti-Human CD62L DREG-56 antibody recognizes the same antigen as LAM-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (HEV) in frozen

sections of peripheral, but not mucosal lymphoid tissue.

BD Horizon™ BV480 Mouse Anti-Human CD45

CD45 is encoded by the PTPRC (Protein tyrosine phosphatase receptor type C) gene. BD Horizon™ BV480 Mouse Anti-Human CD45 is present on all human leukocytes including lymphocytes, monocytes, granulocytes, eosinophils, and thymocytes. CD45 is absent from circulating erythrocytes, platelets, or mature erythroid cells of bone marrow and non-hemopoietic tissues.

BD Horizon™ BV480 Mouse Anti-Human CD123

IL-3Rα is expressed on a subset of peripheral blood dendritic cells, myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. BD Horizon™ BV480 Mouse Anti-Human CD123 is the 70 kDa IL-3 receptor α chain (IL-3Rα) that associates with the 120-140 kDa β subunit (CD131/Common β-chain/βc) to form the functional IL-3 receptor complex.

BD Horizon™ BV480 Mouse Anti-Human CD14

CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB. BD Horizon™ BV480 Mouse Anti-Human CD14-specific antibody reacts with interfollicular macrophages, reticular dendritic cells and some Langerhans cells.

BD Horizon™ BV480 Rat Anti-Mouse I-A/I-E

M5/114.15.2 monoclonal antibody recognizes a polymorphic determinant shared by I-A[b], I-A[d], I-A[q], I-E[d], I-E[k] MHC class II alloantigens that can be expressed by B cells, dendritic cells, monocytes, macrophages and activated T cells. BD Horizon™ BV480 Rat Anti-Mouse I-A/I-E also reacts with cells from mice of the H-2[p] and H-2[r] haplotypes, and it is non-reactive with cells from NOD (H-2[g7]) mice.

BD Horizon™ BV480 Mouse Anti-Human CD8

CD8 is expressed by majority of thymocytes, by subpopulations of αβ T cells and γδ T cells and by some NK cells. BD Horizon™ BV480 Mouse Anti-Human CD8 plays important roles in T cell activation and selection.

BD Horizon™ BV480 Mouse Anti-NHP CD45

D058-1283 is a CD45 monoclonal antibody specific for non-human primate leucocytes. BD Horizon™ BV480 Mouse Anti-NHP CD45 antibody reacts with baboon, Rhesus and Cynomolgus Macaque leucocytes in a similar pattern to CD45 binding to leukocyte common antigen (LCA) on human cells.  

BD Horizon™ BV480 Mouse Anti-Human CD45RA

CD45RA is expressed on approximately 40-50% of peripheral CD4+ T cells, 50% of peripheral CD8+ T cells and on a portion of B cells and monocytes. BD Horizon™ BV480 Mouse Anti-Human CD45RA antigen is expressed by naive and activated T cells. CD45RA-specific antibodies are useful for the study of the suppressor/inducer subpopulation of CD4+ lymphocytes.

BD Horizon™ BV480 Mouse Anti-Human CD1a

CD1a is expressed on cortical thymocytes, dendritic cells and Langerhans cells. BD Horizon™ BV480 Mouse Anti-Human CD1a has structural similarities to the MHC class I antigen, and plays a role in antigen presentation. 

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