Thermo Fisher Scientific Oligonucleotide Synthesis Chemicals
From Catalog to Custom Synthesis Chemicals
Everyone’s biosynthesis needs are different, whether you're engaged in research, scale-up, or production. When you’re looking for high-purity Thermo Scientific™ catalog chemicals or your work requires customized chemicals and blends, our team of experts will help provide you with the right chemicals, blends, and volumes to meet your precise specifications.
Elevate Your Investigations
Support the synthesis and purification of your oligonucleotides and peptides with reliable, high-purity chemicals available in catalog and bulk formats.
- Solvents (extra-dry and peptide synthesis, LC/LC-MS, and ACS grade)
- Reagents (coupling, protection, deprotection, and deblocking agents)
- Cap A, Cap B
- Activators and oxidizers
Supporting Bench-to-Production Applications
Whether you are in research and discovery or planning to scale up for commercial manufacturing, count on the Thermo Fisher Scientific collection of 80,000+ chemicals available through an extensive global network of 3,500+ manufacturers.
Custom and Bulk Services Overview Video
Trust Thermo Fisher Scientific experts to help you find high-purity catalog and customized chemicals and blends that meet your precise specifications.
Custom and Bulk Services

Bulk/High-Volume Services
Solvents and Alternatives
Improve efficiency and safety with high-volume solvent delivery services that align with your sustainability goals. Explore a range of grades, volumes, and container options to suit your analytical and manufacturing requirements.
Large-Quantity Offerings
Choose from a wide variety of catalog chemicals in larger sizes and formats to enable your scale-up. These chemicals can be tested, packaged, and delivered according to your requirements.

Custom Chemical Services
Blends and Syntheses
Let us help you optimize your product and process, whether you’re producing custom blends, synthesizing complex organic building blocks, or looking to develop a scalable route. By accessing our extensive database of production methods for over 8,000 compounds—developed through 50 years of experience in custom manufacturing—our experts can provide the support you need.
Custom Pack Sizes, Packaging, and Labels
Help improve handling, storage, and product integrity by selecting the material, weight, packaging, and labeling to meet your specifications.
Whether you're engaged in research or scaling up for production, count on Thermo Fisher Scientific customizable chemicals and blends for your oligonucleotide synthesis. With over 65 years of experience in chemical manufacturing, Thermo Fisher offers 92,000+ chemicals through an extensive global network of 3,500+ manufacturers. Trust their expert team to tailor your order to meet your exact specifications and deliver it to your location by the date you need it.
A Reliable Service That Meets Your High Standards
Rely on Thermo Fisher to support your bench-to-production oligonucleotide applications. Once the team establishes your chemical needs, they will manufacture the high-purity, high-yield products you require to optimize your results, including:
- Activators
- Cap A and Cap B solutions
- Deblocking agents
- Extra-dry solvents
- Oxidizers
To precisely meet your specifications and deliver your chemicals as promised while helping to protect the environment, Thermo Fisher abides by these four operational pillars:
Quality and Compliance
Through the custom oligonucleotide synthesis chemicals and blends service, Thermo Fisher produces compliant-ready products, which are fully traceable and come with complete documentation. They are manufactured in a world-class ISO-9001 facility using a strict quality control process.
Custom quality control is available, and you may also request lot validation samples. To help ensure there is no potential for cross-contamination, your chemicals will be packaged in a fleet of returnable containers that will be designated for your use only.
Global Supply
Dedicated Thermo Fisher teams are committed to meeting your precise requirements across continents. This includes supporting logistics, transportation, and container fleet management to maximize efficiency. Products are distributed through a global network of warehouses and can be delivered quickly to you: whenever and wherever you need them.
Partnership
As your partner, Thermo Fisher believes in maintaining clear and open lines of communication in order to manage projects effectively. A dedicated team will consult with you about your needs and offer technical expertise when necessary, supporting you throughout the entire order and fulfilment process.
Sustainability
You can help meet your sustainability goals and protect the environment by taking advantage of the Thermo Fisher returnable container service, which reduces the amount of glass and cardboard you need to dispose of. For example, with each 200 L returnable container, you can eliminate almost 200 lb./90 kg of glass and cardboard waste.
The returnable container program dedicates a fleet of drums and/or barrels to your chemicals so you can rest assured your order won’t be exposed to cross-contamination. This service also includes the cleaning, maintaining, and refilling of your empty drums/barrels, which can not only reduce your hazardous disposal costs, but can also eliminate the need for rinsing at your site.
The program works like this: After you place your order, your chemicals are manufactured then delivered to you in a reusable container. Once you have emptied the container, you can arrange a time for Thermo Fisher to pick it up. The drum/barrel then gets cleaned, validated, and refilled for shipment back to you.
Peptides Synthesis
Explore catalog, custom, and bulk chemicals—including greener options—in a variety of grades to support your peptide synthesis and purification.
Maintain Purity and Efficiency with the Right Solvents
Solvents are critical to your peptide synthesis workflow. Maintain confidence in the purity and efficiency of your reactions by choosing high-grade Thermo Fisher chemicals for your work. To help reach your sustainability goals, alternative, greener solvents and blends are also available through the custom and bulk chemicals program.
Learn more about Thermo Fisher peptide synthesis solvents:
Secure Your Sequence and Structure with Reliable Reagents
Enhance the precision and efficiency of your peptide synthesis with coupling, protection, and deprotection reagents that also help secure your peptide chain sequencing and structure.
Learn more about Thermo Fisher reagents for peptide synthesis:
Supporting Every Step of Your Peptide Synthesis Journey
Support efficient, reliable, and high-quality peptide synthesis for your research and production applications with Thermo Fisher catalog products and custom and bulk services.
Wide-Ranging, High-Purity, High-Performance Possibilities
Engage in high-fidelity, high-performance peptide synthesis with a comprehensive range of high-purity chemicals, which are also available in more sustainable alternatives.
- Reaction, washing, and purification solvents
- Coupling, protection, and deprotection reagents
- Amino acids
Enable Efficient Delivery of Consistent Results Across Batches
Optimize your synthesis process and achieve reproducibility with chemicals designed to deliver consistent results across different batches. Manufactured in world-class ISO-9001 facilities, they also help reduce reaction times and improve yield.
Simple to Scale and Compatible with Automation Equipment
Fulfill your small-scale research or large-scale production needs with catalog or bulk chemicals. If you’re looking to improve workflow efficiency, they are compatible with automated peptide synthesizers.
Get Expert Assistance
Let Thermo Fisher experts help you troubleshoot and optimize your peptide synthesis protocols. They are skilled at providing consultation and project management services and offer product support and informative resources.
If you need help finding the right chemicals and blends for your oligonucleotide and peptide synthesis, count on Thermo Fisher Scientific experts to support your project. Their extensive knowledge has been developed and cultivated through 50 years of experience in custom manufacturing.

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