Cell Culture Solutions for Bioprocessing

Monoclonal antibody production is a cornerstone of the biopharmaceutical industry, and success depends on more than yield. Companies need CHO cell culture solutions that deliver high titers, consistent product quality, and reliable scalability. The right media and feed system reduces variability, streamlines biomanufacturing processes, and helps therapies advance efficiently from development to commercial production.

Gibco™ Efficient-Pro™ Medium and the broader portfolio of Gibco animal-origin-free solutions are designed to meet these needs. From viral culture to microbial fermentation and cell handling, this advanced, next-generation monoclonal antibody medium is designed to work optimally with CHO cell lines. The medium pairs with two innovative, single-part feeds, formulated specifically for use in key bioproduction cell lines.

Developed with chemically defined and animal-origin-free formulations, Gibco Efficient-Pro medium and feeds have been designed to help you maintain batch-to-batch consistency. Additionally, through Thermo Fisher Scientific’s global network of harmonized facilities and manufacturing redundancy, you can reduce the risk of supply disruption, helping you focus on your process.

Vaccine manufacturers need reliable upstream tools that deliver consistent performance, regulatory confidence, and scalability across diverse platforms. From viral propagation to microbial fermentation and cell culture, every step requires solutions that reduce variability, streamline downstream processing, and support rapid scale-up.

Consistency and scalability are critical to turning vaccine innovation into reliable, regulatory-ready manufacturing.

Vaccine production faces constant pressure to deliver higher yields, consistent quality, and faster scale-up, all while meeting strict regulatory standards. Traditional methods can introduce variability, increase purification burdens, or slow manufacturing timelines. Companies need reliable, animal-origin-free solutions that simplify workflows, reduce risk, and help ensure every stage—from viral growth to microbial fermentation—occurs with consistency and confidence.

Gibco delivers a portfolio of trusted, animal-origin-free solutions designed to simplify and strengthen vaccine manufacturing. From viral culture to microbial fermentation and cell handling, their media and reagents are engineered for consistency, regulatory alignment, and scalability.

• Serum-free media for viral propagation provide reliable growth in widely used production cell lines while minimizing protein contaminants to ease downstream purification
• Flexible formats, including liquid and AGT™ granular media, allow you to scale seamlessly from research through commercial manufacturing
• Chemically defined microbial fermentation media support high-yield plasmid DNA production, enabling DNA and RNA vaccine platforms with reproducible quality
• Animal-origin-free enzymes for cell dissociation reduce contamination risks while maintaining healthy, viable cultures that are essential for vaccine workflows

Together, Gibco solutions give vaccine developers the confidence to innovate, scale, and deliver safer, more effective products more efficiently.