1,1'-Carbonyldiimidazole, 97%, Thermo Scientific Chemicals

Description

Peptide coupling reagent1,1'-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohols and amines into carbamates, esters, and ureas. It is involved in the preparation of formylized imidazole by reaction with formic acid. Further, it is used in the synthesis of dipolar polyamides compounds. In addition to this, it is considered as an equivalent of phosgene and used to prepare asymmetric bis alkyl carbonate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Peptide coupling reagent1,1′-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohols and amines into carbamates, esters, and ureas. It is involved in the preparation of formylized imidazole by reaction with formic acid. Further, it is used in the synthesis of dipolar polyamides compounds. In addition to this, it is considered as an equivalent of phosgene and used to prepare asymmetric bis alkyl carbonate.

Solubility
Soluble in dimethylformamide.

Notes
Store in a cool place. Incompatible with water, strong acids, strong oxidizing agents, strong bases and amines.

Specifications

• Melting Point: 116°C to 120°C
• pH: 7.7
• Assay Percent Range: 97%
• Quantity: 10 g
• UN Number: UN3263
• Beilstein: 6826
• Sensitivity: Moisture sensitive
• Merck Index: 14,1819
• Solubility Information: Soluble in dimethylformamide.
• IUPAC Name: di(imidazol-1-yl)methanone
• Formula Weight: 162.15
• Percent Purity: 97%
• Chemical Name or Material: 1,1'-Carbonyldiimidazole

Safety and Handling

Hazard Category	H302-H314-H335
Hazard Statement	GHS H Statement H314-H318-H302 Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed.
Precautionary Statement	P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S.
EINECSNumber	208-488-9
TSCA	Yes
storageNote1	Moisture sensitive
Recommended Storage	Ambient temperatures; Store under Argon

SDS

RUO – Research Use Only