1-(2-Aminoethyl)piperidine, 98%

Description

CAS: 27578-60-5 | C7H16N2 | 128.219 g/mol

1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

Solubility
Partly miscible in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents, acid chlorides and acid anhydrides. It is sensitive to air.

Specifications

Chemical Identifiers

• CAS: 27578-60-5
• Molecular Formula: C7H16N2
• Molecular Weight (g/mol): 128.219
• MDL Number: MFCD00006516
• InChI Key: CJNRGSHEMCMUOE-UHFFFAOYSA-N
• Synonym: n-2-aminoethyl piperidine, 1-2-aminoethyl piperidine, 2-piperidin-1-yl ethanamine, 2-piperidin-1-yl ethan-1-amine, 1-piperidineethanamine, 2-piperidinoethylamine, 2-1-piperidinyl ethanamine, 2-1-piperidinyl ethylamine, n-aminoethylpiperidine, 2-piperidino-1-ethanamine
• PubChem CID: 33944
• IUPAC Name: 2-piperidin-1-ylethanamine
• SMILES: C1CCN(CC1)CCN

• Density: 0.903
• Boiling Point: 185°C to 186°C
• Flash Point: 57°C (134°F)
• Refractive Index: 1.474
• Quantity: 25 g
• UN Number: UN2733
• Beilstein: 103469
• Sensitivity: Air Sensitive
• Solubility Information: Partly miscible in water.
• Formula Weight: 128.22
• Percent Purity: 98%
• Chemical Name or Material: 1-(2-Aminoethyl)piperidine

Safety and Handling

Hazard Category	H226-H314
Hazard Statement	GHS H Statement H314-H318-H226 Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapour.
Precautionary Statement	P210-P233-P240-P241-P242-P243-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: AMINES, FLAMMABLE, CORROSIVE, N.O.S.
EINECSNumber	248-540-8
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only