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(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98%, Thermo Scientific Chemicals
Description
It finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II, for the preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands, in the synthesis and antitumor agents, in regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
It finds its applications as a reagent for Wittig olefinations with introduction of a 1,3-dioxolane moiety. It is applied as a reactant for the preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione, for microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II, for the preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands, in the synthesis and antitumor agents, in regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization.
Solubility
Soluble in water (20°C).
Notes
Hygroscopic. Store away from water/moisture and oxidizing agents. Store under inert gas. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications
| Melting Point | 186°C to 189°C |
| Quantity | 10 g |
| Sensitivity | Hygroscopic |
| Solubility Information | Soluble in water (20°C). |
| Formula Weight | 429.3 |
| Percent Purity | 98% |
| Chemical Name or Material | (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide |
Safety and Handling
| Hazard Category | H302+H312+H332-H315-H319-H335 |
| Hazard Statement | GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
| Precautionary Statement | P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c |
| EINECSNumber | 257-977-3 |
| TSCA | No |
| Recommended Storage | Keep cold |
RUO – Research Use Only
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