1,4-Dioxane, 99+%, stab. with ca 5-10ppm BHT

Description

CAS: 123-91-1 | C4H8O2 | 88.106 g/mol

1,4-Dioxane is used as a stabilizer for 1,1,1-trichloroethane and chlorinated solvents. It acts as a solvent for cellulose acetate, ethyl cellulose, benzyl cellulose, resins, oils, waxes, dyes, other organic and inorganic compounds. It acts as a substitute for tetrahydrofuran due to its higher boiling point and lower toxicity. Further, it is used as an internal standard for proton NMR spectroscopy in deuterium oxide. It plays an important role in liquid scintillation counting in biological procedures, and as a wetting and dispersing agent in textile processing. It is involved in the preparation of dimethylmagnesium by reacting with methylmagnesium bromide, and in the preparation of histological sections for microscopic examination.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,4-Dioxane is used as a stabilizer for 1,1,1-trichloroethane and chlorinated solvents. It acts as a solvent for cellulose acetate, ethyl cellulose, benzyl cellulose, resins, oils, waxes, dyes, other organic and inorganic compounds. It acts as a substitute for tetrahydrofuran due to its higher boiling point and lower toxicity. Further, it is used as an internal standard for proton NMR spectroscopy in deuterium oxide. It plays an important role in liquid scintillation counting in biological procedures, and as a wetting and dispersing agent in textile processing. It is involved in the preparation of dimethylmagnesium by reacting with methylmagnesium bromide, and in the preparation of histological sections for microscopic examination.

Solubility
Miscible with water, organic solvents, aromatic hydrocarbons and oils.

Notes
Hygroscopic. Incompatible with oxygen, oxidizing agents, halogens, reducing agents, perchlorates and trimethylaluminum.

Specifications

Chemical Identifiers

• CAS: 123-91-1
• Molecular Formula: C4H8O2
• Molecular Weight (g/mol): 88.106
• MDL Number: MFCD00006571
• InChI Key: RYHBNJHYFVUHQT-UHFFFAOYSA-N
• Synonym: dioxane, p-dioxane, 1,4-diethylene dioxide, diethylene ether, dioxan, 1,4-dioxacyclohexane, diethylene dioxide, dioxanne, di ethylene oxide, tetrahydro-p-dioxin
• PubChem CID: 31275
• ChEBI: CHEBI:47032
• IUPAC Name: 1,4-dioxane
• SMILES: C1COCCO1

• Melting Point: 11.8°C
• Density: 1.034
• Boiling Point: 100°C to 102°C
• Quantity: 2500 g
• Odor: Ether-like
• Refractive Index: 1.422
• UN Number: UN1165
• Beilstein: 102551
• Merck Index: 14,3300
• Solubility Information: Miscible with water,organic solvents,aromatic hydrocarbons and oils.
• Formula Weight: 88.11
• Percent Purity: ≥99%
• Chemical Name or Material: 1,4-Dioxane, stabilized with ≈5 to 10ppm BHT

Safety and Handling

Hazard Category	H225-H319-H335-H336-H350-H373
Hazard Statement	GHS H Statement H225-H351-H319-H335 Highly flammable liquid and vapour. Suspected of causing cancer. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280i-P281-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: DIOXANE
EINECSNumber	204-661-8
RTECSNumber	JG8225000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only