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Tocris Bioscience™ 10-Cl-BBQ

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Quantity:
5 mg
25 mg
Description
10-Cl-BBQ is a potent aryl hydrocarbon receptor (AhR) agonist, discovered as a screening hit (IC50 = 2.6 nM). Directly binds CD4+ T cells to induce AhR-dependent Tregs. Suppresses IL-17 production and prevents insulitis in NOD mice. In vivo half llife ∽ 2 hours, orally bioavailable.
Specifications
Specifications
Chemical Name or Material | 10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one |
CAS | 23982-76-5 |
Quantity | 5 mg |
Molecular Formula | C18H9ClN2O |
Formula Weight | 304.73 |
Purity | 97% |
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