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  5. Tocris Bioscience™ 10-DEBC hydrochloride

Tocris Bioscience™ 10-DEBC hydrochloride
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Catalog No. 255810
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Catalog No. Quantity
25-581-0 10 mg
25-585-0 50 mg
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Catalog No. 25-581-0 Supplier Tocris Bioscience™ Supplier No. 2558/10
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Description

Selective Akt/PKB inhibitor

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ∽ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells.

Chemical Identifiers

CAS 925681-41-0
Molecular Formula C20H26Cl2N2O

Specifications

Quantity 10 mg
Formula Weight 381.34
Purity >99%
Molecular Weight (g/mol) 381.341
Chemical Name or Material 10-DEBC hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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