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10-DEBC hydrochloride, Tocris Bioscience™

Catalog Number 255810
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
925681-41-0
C20H26Cl2N2O
381.341
SVKSJUIYYCQZEC-UHFFFAOYSA-N
Akt Inhibitor X, 10-4′-n-diethylamino butyl-2-chlorophenoxazine, hcl, 10-4'-n,n-diethylamino butyl-2-chlorophenoxazine hydrochloride, 4-2-chlorophenoxazin-10-yl butyl diethylamine hydrochloride, 4-2-chloro-10h-phenoxazin-10-yl-n,n-diethylbutan-1-amine-hydrogen chloride 1/1
16760284
4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine;hydrochloride
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl
This item is not returnable. View return policy
925681-41-0
C20H26Cl2N2O
381.341
SVKSJUIYYCQZEC-UHFFFAOYSA-N
Akt Inhibitor X, 10-4′-n-diethylamino butyl-2-chlorophenoxazine, hcl, 10-4'-n,n-diethylamino butyl-2-chlorophenoxazine hydrochloride, 4-2-chlorophenoxazin-10-yl butyl diethylamine hydrochloride, 4-2-chloro-10h-phenoxazin-10-yl-n,n-diethylbutan-1-amine-hydrogen chloride 1/1
16760284
4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine;hydrochloride
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl

Selective Akt/PKB inhibitor

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ∽ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells.
Quantity 10 mg
Formula Weight 381.34
Percent Purity >99%
Chemical Name or Material 10-DEBC hydrochloride
Recommended Storage Desiccate at +4°C
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