Invitrogen™ Zika Virus NS1 (strain H/PF/2013) Recombinant Rabbit Monoclonal Antibody (HL2567)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA556930

Catalog No. MA556930

Description

Zika Virus NS1 (strain H/PF/2013) Recombinant Monoclonal Antibody for Western Blot

As a member of the Flaviviridae family, ZIKV has a single positive sense RNA genome, which is initially translated as a single polyprotein which is then cleaved post-transitionally into three structural proteins (C, PrM or M, and E) and seven nonstructural (NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5)(1). The glycosated NS1 forms a homodimer inside the cells and is necessary for viral replication and late in infection (2). NS1 is also secreted into the extracellular space as a hexameric lipoprotein particle, which assists the virus in immune evasion and pathogenesis by interacting with components from both innate and adaptive immune systems as well as other host factors (1). Reference 1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456-458. 2) Suthar, M.S., Diamond, M.S. & Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115-128.

Specifications

• Antigen: Zika Virus NS1 (strain H/PF/2013)
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: HL2567
• Conjugate: Unconjugated
• Gene Alias: Zika NS1; ZIKV NS1; ZIKV-NS1
• Immunogen: Synthetic peptide of Zika virus NS1 protein. (strain: H/PF/2013 ).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid