Epredia™ Lab Vision™ 14.3.3σ Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Take advantage of a quality product that delivers accurate results with the Epredia™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1185R1

Catalog No. MS1185R1

Description

14.3.3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14.3.3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14.3.3 and target proteins are strongly influenced by the phosphorylation state of 14.3.3 and the target protein. 14.3.3 σ shares cyclin-Cdk2 binding motifs with different cell cycle regulators, including p107, p130, p21Cip1, p27Kip1, and p57Kip2 and is associated with cyclin-Cdk complexes in vitro and in vivo.

Host Species: Mouse

Clone: 1433S01

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant human 14.3.3σ protein

Molecular Weight: 26-30kDa

Positive Control: HT29 cells, Skin

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: 14.3.3sigma Ab-1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Signal Transduction
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 1433S01
• Formulation: Ready-to-use for IHC (UVLP)
• Immunogen: Recombinant human 1433 sigma protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Prediluted