Invitrogen™ 14-3-3 beta Monoclonal Antibody (05)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA528985

Catalog No. PIMA528985

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Cynomolgus 14-3-3 beta/YWHAB.

14-3-3, a family of acidic and soluble proteins, highly conserved in amino acid sequences from yeast to mammals, is expressed in all eukaryotic cells. Seven isoforms(beta, gamma, epsilon, eta, zeta, sigma and tau/theta) encoded by seven distinct genes are identified in mammals and forms homo- and hetero- dimeric cup-shaped structures. As 14-3-3 is interacted with more than 100 binding partners, it regulates key proteins involved in various biological processes such as signal trans-duction, cell cycle, transcriptional control, cell proliferation, apoptosis, and ion channel physiology. Most 14-3-3 requires phosphorylation of serine or threonine residues in the target sequence. This protein is abundantly expressed in the brain and has been detected in the cerebrospinal fluid of patients with different neurological disorders.

Specifications

• Antigen: 14-3-3 beta
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q4R572
• Gene Symbols: YWHAB
• Immunogen: Recombinant Cynomolgus 14-3-3 beta/YWHAB protein (Met2-Asn244).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Cynomolgus Monkey
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 05
• Conjugate: Unconjugated
• Gene: YWHAB
• Gene Alias: 1300003C17Rik; 14-3-3 alpha; 14-3-3 protein beta; 14-3-3 protein beta/alpha; 14-3-3 protein beta/alpha, N-terminally processed; 14-3-3 protein beta-subtype; 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide; brain protein 14-3-3, beta isoform; epididymis secretory protein Li 1; GW128; HEL-S-1; HS1; hypothetical protein GW128; KCIP 1; KCIP1; KCIP-1; Prepronerve growth factor RNH-1; protein 1054; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; QccE-16215; RP1-148E22.1; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide; tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide; tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; unnamed protein product; YWHAA; Ywhab
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 101926442
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid