Invitrogen™ 14-3-3 epsilon Polyclonal Antibody

Catalog No.	Quantity
PIPA587995	100 μL

Catalog No. PIPA587995 Supplier Invitrogen™ Supplier No. PA587995

Description

Rabbit Polyclonal Antibody

Immunogen sequence: KGGEDKLKMI REYRQMVETE LKLICCDILD VLDKHLIPAA NTGESKVFYY KMKGDYHRYL AEFATGNDRK EAAENSLVAY KAASDIAMTE L Positive Samples: HeLa, HepG2, NIH/3T3, SH-SY5Y, Mouse kidney, Rat liver; Cellular Location: Cytoplasm, Melanosome.

14-3-3 epsilon belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

Specifications

• Antigen: 14-3-3 epsilon
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.64 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene: YWHAE
• Gene Accession No.: P62258, P62259, P62260
• Gene Alias: 14-3-3 epsilon; 14-3-3 protein epsilon; 14-3-3E; AU019196; epididymis luminal protein 2; HEL2; KCIP-1; MDCR; MDS; mitochondrial import stimulation factor (MSF) L subunit; mitochondrial import stimulation factor L subunit; MSF L; protein kinase C inhibitor protein-1; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activatioprotein epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activatioprotein, epsilon polypeptide; Ywhae
• Gene Symbols: YWHAE
• Host Species: Rabbit
• Immunogen: Recombinant protein (or fragment).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22627, 29753, 7531
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG