14-3-3 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2E10A3, Proteintech

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-6500	Proteintech Group Inc 660611IG150UL	150 μL

Description

66061-1-Ig recognizes 14-3-3 tau (YWHAQ), eta (YWHAH), and zeta (YWHAZ), but not epsilon (YWHAE).

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5′ UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Specifications

• Antigen: 14-3-3
• Concentration: 0.71 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: 14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 14-3-3 tau, HS1, Protein HS1, YWHAQ
• Gene Symbols: Ywhaq
• Isotype: IgG1
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 2E10A3
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mouse, Pig, Rat
• Gene Accession No.: P27348, P68254, P68255
• Gene ID (Entrez): 100048964, 10971, 22630, 25577
• Immunogen: 14-3-3 Fusion Protein Ag6055
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: YWHAQ