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2,2,2-Trifluoroethanol, 99+%, Thermo Scientific Chemicals
Description
Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.
Solubility
Miscible with water, ethers, ketones, alcohols and chloroform.
Notes
Moisture sensitive.
Specifications
Melting Point | -44°C |
Density | 1.391 |
Boiling Point | 74°C to 75°C |
Flash Point | 29°C (84°F) |
Refractive Index | 1.29 |
Linear Formula | CF3CH2OH |
Quantity | 50 g |
UN Number | UN1992 |
Beilstein | 1733203 |
Solubility Information | Miscible with water,ethers,ketones,alcohols and chloroform. |
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Safety and Handling
Hazard Category | H226-H301+H331-H318-H360F-H373 |
Hazard Statement | GHS H Statement H301-H311-H318-H226-H332-H315-H335 Toxic if swallowed. Toxic in contact with skin. Causes serious eye damage. Flammable liquid and vapor. Harmful if inhaled. Causes skin irritation. May cause respiratory irritation. |
Precautionary Statement | P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P281-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P310-P311-P330-P370+P378q-P501c |
DOTInformation | Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, TOXIC, N.O.S. |
EINECSNumber | 200-913-6 |
RTECSNumber | KM5250000 |
TSCA | Yes |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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