2,2,2-Trifluoroethyl trifluoromethanesulfonate, 95%

Description

CAS: 6226-25-1 | C3H2F6O3S | 232.096 g/mol

2,2,2-Trifluoroethyl trifluoromethanesulfonate is a powerful trifluoroethylating agent which is useful for synthesis of fluorinated amino acids. It is used as a reagent in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2,2-Trifluoroethyl trifluoromethanesulfonate is a powerful trifluoroethylating agent which is useful for synthesis of fluorinated amino acids. It is used as a reagent in thenantioselective preparation of cyclic N-aryl hydroxamic acids via phase-transfer catalyzed alkylation of nitrobenzyl bromides to give nirophenylalanines.

Solubility
Slightly soluble in water.

Notes
Moisture sensitive. Incompatible with oxidizing agents and heat.

Specifications

Chemical Identifiers

• CAS: 6226-25-1
• Molecular Formula: C3H2F6O3S
• Molecular Weight (g/mol): 232.096
• MDL Number: MFCD00671579
• InChI Key: RTMMSCJWQYWMNK-UHFFFAOYSA-N
• Synonym: 2,2,2-trifluoroethyltrifluoromethanesulfonate, 2,2,2-trifluoroethyl triflate, methanesulfonic acid, trifluoro-, 2,2,2-trifluoroethyl ester, trifluoromethanesulfonic acid 2,2,2-trifluoroethyl ester, 2,2,2-trifluoroethyl trifluoromethanesulphonate, 2,2,2-trifluoroethyl trifluorometanesulfonic acid, 2,2,2-trifluoroethyltrifluoromethanesulphonate, 2,2,2-trifluoroethyl trifluoromethane sulfonate, trifluoroethyltriflate, trifluoroethyl triflate
• PubChem CID: 80366
• IUPAC Name: 2,2,2-trifluoroethyl trifluoromethanesulfonate
• SMILES: C(C(F)(F)F)OS(=O)(=O)C(F)(F)F

• Color: Colorless to Yellow
• Density: 1.611 g/mL
• Flash Point: >110°C (230°F)
• Refractive Index: 1.306
• Linear Formula: CF₃SO₃CH₂CF₃
• Quantity: 25 g
• UN Number: UN3265
• Sensitivity: Moisture sensitive
• Solubility Information: Slightly soluble in water.
• Formula Weight: 232.1
• Percent Purity: 95%
• Physical Form: Liquid
• Chemical Name or Material: 2,2,2-Trifluoroethyl trifluoromethanesulfonate

Safety and Handling

Hazard Category	H302+H312+H332-H314-H335
Hazard Statement	GHS H Statement H314-H318-H332 Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if inhaled.
Precautionary Statement	P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Hazard Class: 6.1; Packaging Group: II
RTECSNumber	PB2775000
TSCA	No
storageNote1	2° to 8°C
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only