2-Chloro-4,6-dimethoxy-1,3,5-triazine, 98%

Description

CAS: 3140-73-6 | C5H6ClN3O2 | 175.57 g/mol

2-Chloro-4,6-dimethoxy-1,3,5-triazine is used as a peptide coupling agent for the purification of peptides. It is used in the synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride through coupling with N-methylmorpholine in tetrahydrofuran. Further, it plays an important role in the production of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, through reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine. In addition to this, it is involved in the preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts through reaction with various tertiary amines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Chloro-4,6-dimethoxy-1,3,5-triazine is used as a peptide coupling agent for the purification of peptides. It is used in the synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride through coupling with N-methylmorpholine in tetrahydrofuran. Further, it plays an important role in the production of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, through reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine. In addition to this, it is involved in the preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts through reaction with various tertiary amines.

Solubility
Soluble in water, chloroform and methanol.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 3140-73-6
• Molecular Formula: C5H6ClN3O2
• Molecular Weight (g/mol): 175.57
• MDL Number: MFCD00075607
• InChI Key: GPIQOFWTZXXOOV-UHFFFAOYSA-N
• Synonym: cdmt, 1,3,5-triazine, 2-chloro-4,6-dimethoxy, 2-chloro-4,6-dimethoxy-s-triazine, 2-chloro-4,6-dimethoxy-1,3,5 triazine, pubchem20734, acmc-1cnh7, ksc567a8j, 2-chloro-4,6-dimethoxy s-triazine, 1,5-triazine, 2-chloro-4,6-dimethoxy
• PubChem CID: 18450
• IUPAC Name: 2-chloro-4,6-dimethoxy-1,3,5-triazine
• SMILES: COC1=NC(OC)=NC(Cl)=N1

• Melting Point: 75°C to 79°C
• Boiling Point: 99°C to 100°C (1 mmHg)
• Quantity: 5 g
• Beilstein: 148988
• Solubility Information: Soluble in water,chloroform and methanol.
• Formula Weight: 175.58
• Percent Purity: 98%
• Chemical Name or Material: 2-Chloro-4,6-dimethoxy-1,3,5-triazine

Safety and Handling

Hazard Category	H302-H317-H318-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P272-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P333+P313-P363-P501c
DOTInformation	Hazard Class: 9; Packaging Group: III
EINECSNumber	221-541-0
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only