2-Fluoro-4-methylaniline, 99%

Description

CAS: 452-80-2 | C7H8FN | 125.15 g/mol

2-Fluoro-4-methylaniline is used in the preparation of 6-chloro-5-fluoroindole via Leimgruber-Batcho reaction. It is also used in the preparation of an (S)-amino alcohol, 2-amino-3-(2-fluoro-4-methylphenyl)-propan-1-ol.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Fluoro-4-methylaniline is used in the preparation of 6-chloro-5-fluoroindole via Leimgruber-Batcho reaction. It is also used in the preparation of an (S)-amino alcohol, 2-amino-3-(2-fluoro-4-methylphenyl)-propan-1-ol.

Solubility
Not miscible in water.

Notes
Store in a cool, dry, conditions in well sealed container. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 452-80-2
• Molecular Formula: C7H8FN
• Molecular Weight (g/mol): 125.15
• MDL Number: MFCD00040975
• InChI Key: ZQEXBVHABAJPHJ-UHFFFAOYSA-N
• Synonym: 2-fluoro-4-methyaniline, 2-fluoro-p-toluidine, 4-amino-3-fluorotoluene, p-toluidine, 2-fluoro, benzenamine, 2-fluoro-4-methyl, 2-fluoro-4-methyl aniline, 2-fluoro-4-methyl-aniline, 2-fluoro-4-methyl-phenylamine, 2-fluoro-4-methylphenylamine, benzenamine, 2-fluoro-4-methyl-9ci
• PubChem CID: 67984
• IUPAC Name: 2-fluoro-4-methylaniline
• SMILES: CC1=CC=C(N)C(F)=C1

• Density: 1.108
• Boiling Point: 70°C to 71°C (7 mmHg)
• Flash Point: 79°C (174°F)
• Refractive Index: 1.533
• Quantity: 25 g
• UN Number: UN2810
• Beilstein: 2637578
• Solubility Information: Not miscible in water.
• Formula Weight: 125.15
• Percent Purity: 99%
• Chemical Name or Material: 2-Fluoro-4-methylaniline

Safety and Handling

Hazard Category	H227-H301+H311+H331-H315-H319-H335
Hazard Statement	GHS H Statement H311-H373-H227-H302-H332-H315-H319 Toxic in contact with skin. May cause damage to organs through prolonged or repeated exposure. Combustible liquid. Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P210-P235-P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P311-P312-P330-P332+P313-P361-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S.
RTECSNumber	XU6650000
TSCA	No
Recommended Storage	Ambient temperatures

RUO – Research Use Only