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Tocris Bioscience™ 2A3
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Catalog No. 737610
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10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable

2A3 is an electrophilic chemical probe that acylates the 2'-OH in the RNA backbone. 2A3 can be used for RNA SHAPE-MaP experiments in cell lines or live bacteria. It labels single-stranded or flexible regions more than folded regions (SHAPE methodology) and enables analysis of RNA secondary structures at single nucleotide resolution. For intracellular experiments, 2A3 has higher signal-to-noise ratio and prediction accuracy than NAI (Cat. No. 7004). 2A3 is cell permeable, and can probe both gram-positive and gram-negative bacteria.

Specifications

Chemical Name or Material (2-Aminopyridin-3-yl)(1 H-imidazol-1-yl)methanone
Quantity 10 mg
Target DNA, RNA and Protein Synthesis Compounds
Molecular Formula C9H8N4O
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