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Tocris Bioscience™ 3',2'-cGAMP sodium salt
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Catalog No. 7718359U
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359 μg
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7718359U 359 μg
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Catalog No. 7718359U Supplier Tocris Bioscience™ Supplier No. 7718/359U
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Description

Induces expression of STING and STING-related genes; antiviral

3',2'-cGAMP sodium salt is a second messenger in the antiviral immune response in Drosophila melanogaster and in bacteria. 3',2'-cGAMP is selective for Drosophila stimulator of interferon genes (dSTING); induces expression of STING and STING-related genes. After injection of drosophila C virus dsRNA into Drosophila, 3',2'-cGAMP activates STING-dependent antiviral immunity in vivo, reduces viral RNA load and increases survival. In bacteria 3',2'-cGAMP activates DNA degradation of AsCap5 and LlCap5.

Specifications

Chemical Name or Material 3 ',2 '-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
Quantity 359 μg
Target STING/TMEM173
Molecular Formula C20H22N10Na2O13P2
Purity 0.98
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