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Tocris Bioscience™ 3',3'-cGAMP sodium salt

Catalog No. 5946359U
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359 μg
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Catalog No. Quantity
59-463-59U 359 μg
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Catalog No. 59-463-59U Supplier Tocris Bioscience™ Supplier No. 5946/359U
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Description

STING agonist

3',3'-cGAMP sodium salt is a STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice.

This product is sold in units of 359μg, equivalent to 0.5μmol.

Specifications

Chemical Name or Material 3′,3′-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
CAS 2407516-83-8
Synonym endoplasmic reticulum IFN stimulator, Endoplasmic reticulum interferon stimulator, ERIS, FLJ38577, hMITA, Mediator of IRF3 activation, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membr
Quantity 359 μg
Target STING/TMEM173
Molecular Formula C20H22N10Na2O13P2
Formula Weight 718.37
Purity >98%
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