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Tocris Bioscience™ 3-Bromopyruvate
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Catalog No. 7512100
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100 mg
Catalog No.
75-121-00 100 mg
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Catalog No. 75-121-00

Supplier: Tocris Bioscience™ 7512/100

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Description

MCT1 inhibitor; also inhibits hexokinase II

3-Bromopyruvate is a monocarboxylate transporter (MCT1) inhibitor (IC50 = 14.7 μM, 24.2 μM and 28.6 μM in SiHa, UM-UC-3, and HCT-116 human cancer cell lines, respectively). 3-Bromopyruvate shows antitumor activity in vitro and in vivo. 3-Bromopyruvate is also an inhibitor of hexokinase II, and decreases apoptosis in dopaminergic neurons in Parkinson's disease models in vitro and in vivo.

Specifications

Chemical Name or Material 3-Bromo-2-oxopropanoic acid
CAS 1113-59-3
Quantity 100 mg
Target Monocarboxylate Transporter Inhibitors
Molecular Formula C3H3BrO3
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