3-Chloropropanesulfonyl chloride, 98+%, Thermo Scientific Chemicals

Description

3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors. It is also used in the generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams and sultones. It is mainly used for the synthesis of pharmaceutical intermediates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors. It is also used in the generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams and sultones. It is mainly used for the synthesis of pharmaceutical intermediates.

Solubility
Soluble in dichloromethane, ethyl Acetate and hexane.

Notes
Store at -20°C. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Moisture sensitive. Keep away from alcohols, strong bases, oxidizing agents.

Specifications

• Density: 1.456
• Boiling Point: 70°C (0.5 mmHg)
• Flash Point: >110°C (230°F)
• Refractive Index: 1.49
• Linear Formula: Cl(CH₂)₃SO₂Cl
• Quantity: 10 g
• UN Number: UN3265
• Beilstein: 1754119
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in dichloromethane,ethyl Acetate and hexane.
• Formula Weight: 177.05
• Percent Purity: ≥98%
• Chemical Name or Material: 3-Chloropropanesulfonyl chloride

Safety and Handling

Hazard Category	H314
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	216-646-3
RTECSNumber	TZ6670000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only