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Invitrogen™ 3-Methylcytosine Polyclonal Antibody

Catalog No. PA540098
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50 μg
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PA540098 50 μg
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Catalog No. PA540098 Supplier Invitrogen™ Supplier No. PA540098
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Description

Rabbit Polyclonal Antibody

3-Methylcytosine Polyclonal Antibody for ARRAY

3-methylcytosine arises by erroneous methylation of DNA through spontaneous exposure to endogenous S-adenosyl methionine (SAM). Since the N3-position in cytosine is protected in double stranded DNA, this phenomenon mainly occurs in single stranded DNA. The resulting 3-mC is toxic and mutagenic and increased levels of 3-mC seem to impair cell proliferation. Therefore, it has to be repaired by the cell. This is established by oxidative demethylation, which is catalyzed by the AlkB protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen 3-Methylcytosine
Applications Peptide Array
Classification Polyclonal
Concentration 1.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% ProClin 300, 0.05% sodium azide; pH 7.4
Gene Alias 3mc; 3-mC; 3-meC; 3-Methyl-cytosine; C5H7NO3
Host Species Rabbit
Immunogen Human BSA-conjugated 3-methylcytosine (3-mC).
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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