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Invitrogen™ 4-aminobiphenyl DNA Monoclonal Antibody (4C11)
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Catalog No. AMPA6590
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100 μL
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Catalog No. Quantity
AMPA6590 100 μL
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Catalog No. AMPA6590 Supplier Invitrogen™ Supplier No. MA116590
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Description

Mouse Monoclonal Antibody

4-aminobiphenyl DNA Monoclonal Antibody for ICC/IF, IHC, ELISA

4-aminoBiphenyl (4-ABP) is an aromatic amine (arylamine). 4-ABP can be found as a constituent of tobacco smoke, in the form of an environmental carcinogen. It is metabolized by hepatic cytochrome P4501A2 to yield a direct-acting mutagen known as N-hydroxy-aminobiphenyl. Yet, the accumulation of biologically active metabolites is dependent on the activation and detoxification of N-acetylation. 4-ABP has been shown to be a bladder carcinogen in humans and rodents. As well as genetic factors, 4-ABP may also play a role in breast cancer. It is hypothesized that smokers may have higher levels of DNA adducts than non-smokers and that the role of 4-ABP-DNA adducts and their relationship to tobacco exposure may be related to breast tumorigenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen 4-aminobiphenyl DNA
Applications ELISA, Immunohistochemistry, Immunocytochemistry
Classification Monoclonal
Clone 4C11
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.1% sodium azide
Gene Alias 4-AMBP DNA; 4-aminobiphenyl DNA
Host Species Mouse
Immunogen 4-amino biphenyl DNA.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Target Molecule Chemical
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