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Alfa Aesar™ 4-Chloro-7-nitrobenzofurazan, 99%
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Quantity:
5g
25g
Description
Applications
4-Chloro-7-nitrobenzofurazan is used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. It is utilized in the preparation of fluorescent phospholipid-derivative, hydroxynaphthofurazan and 4-chloro-7-nitrobenzofurazan- didecanoylphosphatidylethanolamine. It serves as a fluorescent reagent to label free sulfhydryls and N-terminals within proteins and trapping agent for cysteine sulfenic acid. It is a sensitive chromogenic and fluorogenic reagent. It reacts with trans-1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene (Danishefsky′s diene) to prepare regioselectively the silyl enol ether. Further, it is used to label peptides, proteins and other biomolecules. In addition it is used in the synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, functionalized hydroxynaphthofurazan and 7-nitrobenzofurazan (NBD)-labeled maleimide.
Solubility
Soluble in methanol, dimethylsulfoxide, dimethylformamide and chloroform.
Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
4-Chloro-7-nitrobenzofurazan is used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. It is utilized in the preparation of fluorescent phospholipid-derivative, hydroxynaphthofurazan and 4-chloro-7-nitrobenzofurazan- didecanoylphosphatidylethanolamine. It serves as a fluorescent reagent to label free sulfhydryls and N-terminals within proteins and trapping agent for cysteine sulfenic acid. It is a sensitive chromogenic and fluorogenic reagent. It reacts with trans-1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene (Danishefsky′s diene) to prepare regioselectively the silyl enol ether. Further, it is used to label peptides, proteins and other biomolecules. In addition it is used in the synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, functionalized hydroxynaphthofurazan and 7-nitrobenzofurazan (NBD)-labeled maleimide.
Solubility
Soluble in methanol, dimethylsulfoxide, dimethylformamide and chloroform.
Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
Specifications
Quantity | 5g |
Melting Point | 96°C to 100°C |
Beilstein | 614212 |
Solubility Information | Soluble in methanol,dimethylsulfoxide,dimethylformamide and chloroform. |
Formula Weight | 199.56 |
Percent Purity | 99% |
Chemical Name or Material | 4-Chloro-7-nitrobenzofurazan |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
H315-H319
EINECSNumber : 233-496-4
RTECSNumber : DF8002400
TSCA : Yes
Recommended Storage : Ambient temperatures