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Alfa Aesar™ 4-Chloro-7-nitrobenzofurazan, 99%

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Quantity:
5g
25g
10199-89-0
C6H2ClN3O3
199.55
MFCD00005808
IGHBXJSNZCFXNK-UHFFFAOYSA-N
4-chloro-7-nitrobenzofurazan,nbd chloride,4-chloro-7-nitrobenzo-2-oxa-1,3-diazole,nbd-cl,7-chloro-4-nitrobenzofurazan,2,1,3-benzoxadiazole, 4-chloro-7-nitro,nbd-chloride,nbd-c 1,1-chloro-4-nitrobenzoxadiazole,4-nitro-7-chlorobenzofurazan
25043
CHEBI:78878
4-chloro-7-nitro-2,1,3-benzoxadiazole
C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]
10199-89-0
C6H2ClN3O3
199.55
MFCD00005808
IGHBXJSNZCFXNK-UHFFFAOYSA-N
4-chloro-7-nitrobenzofurazan,nbd chloride,4-chloro-7-nitrobenzo-2-oxa-1,3-diazole,nbd-cl,7-chloro-4-nitrobenzofurazan,2,1,3-benzoxadiazole, 4-chloro-7-nitro,nbd-chloride,nbd-c 1,1-chloro-4-nitrobenzoxadiazole,4-nitro-7-chlorobenzofurazan
25043
CHEBI:78878
4-chloro-7-nitro-2,1,3-benzoxadiazole
C1=C(C2=NON=C2C(=C1)Cl)[N+](=O)[O-]
Applications
4-Chloro-7-nitrobenzofurazan is used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. It is utilized in the preparation of fluorescent phospholipid-derivative, hydroxynaphthofurazan and 4-chloro-7-nitrobenzofurazan- didecanoylphosphatidylethanolamine. It serves as a fluorescent reagent to label free sulfhydryls and N-terminals within proteins and trapping agent for cysteine sulfenic acid. It is a sensitive chromogenic and fluorogenic reagent. It reacts with trans-1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene (Danishefsky′s diene) to prepare regioselectively the silyl enol ether. Further, it is used to label peptides, proteins and other biomolecules. In addition it is used in the synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, functionalized hydroxynaphthofurazan and 7-nitrobenzofurazan (NBD)-labeled maleimide.

Solubility
Soluble in methanol, dimethylsulfoxide, dimethylformamide and chloroform.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
Quantity 5g
Melting Point 96°C to 100°C
Beilstein 614212
Solubility Information Soluble in methanol,dimethylsulfoxide,dimethylformamide and chloroform.
Formula Weight 199.56
Percent Purity 99%
Chemical Name or Material 4-Chloro-7-nitrobenzofurazan

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362

H315-H319

EINECSNumber : 233-496-4

RTECSNumber : DF8002400

TSCA : Yes

Recommended Storage : Ambient temperatures