4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97%, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
6-(Trifluoromethyl)-4-pyrimidinol is used as building block in chemical synthesis. It may also be used in the synthesis of 10-[3-(6-trifluoromethyl-pyrimidin-4-yloxy)-propoxy]-(20S)-camptothecin.

Solubility
Solubility in methanol (almost transparency). Slightly soluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from heat.

Specifications

Chemical Identifiers

• CAS: 1546-78-7
• Molecular Formula: C5H3F3N2O
• Molecular Weight (g/mol): 164.087
• MDL Number: MFCD00192530
• InChI Key: LVOYSBZJJWPUBD-UHFFFAOYSA-N
• Synonym: 4-hydroxy-6-trifluoromethyl pyrimidine, 4-hydroxy-6-trifluoromethylpyrimidine, 6-trifluoromethyl pyrimidin-4-ol, 6-trifluoromethyl-4-pyrimidinol, 6-trifluoromethyl-1h-pyrimidin-4-one, 6-trifluoromethyl-pyrimidin-4-ol, 6-trifluoromethyl pyrimidin-4 3h-one, 6-trifluoromethyl-4-hydroxypyrimidine, 4 1h-pyrimidinone, 6-trifluoromethyl
• PubChem CID: 1268071
• IUPAC Name: 6-(trifluoromethyl)-1H-pyrimidin-4-one
• SMILES: C1=C(NC=NC1=O)C(F)(F)F

• Melting Point: 169°C to 171°C
• Color: White
• Quantity: 1 g
• Beilstein: 145548
• Formula Weight: 164.09
• Percent Purity: 97%
• Physical Form: Crystalline
• Chemical Name or Material: 4-Hydroxy-6-(trifluoromethyl)pyrimidine

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS