Invitrogen™ 4EBP1 Monoclonal Antibody (4B6G10)

Catalog No.	Quantity
PIMA515313	100 μL

Catalog No. PIMA515313 Supplier Invitrogen™ Supplier No. MA515313

Description

Mouse Monoclonal Antibody

MA5-15313 targets 4E-BP1 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15313 immunogen is purified recombinant fragment of 4E-BP1 expressed in E. Coli.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Specifications

• Antigen: 4EBP1
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 4B6G10
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: Ascites with 0.03% sodium azide
• Gene: EIF4EBP1
• Gene Accession No.: Q13541
• Gene Alias: 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
• Gene Symbols: EIF4EBP1
• Host Species: Mouse
• Immunogen: Purified recombinant fragment of 4E-BP1 expressed in E. Coli.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1978
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1