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Invitrogen™ 4EBP1 Polyclonal Antibody
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Catalog No. PIPA511830
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400 μL
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Catalog No. Quantity
PIPA511830 400 μL
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Catalog No. PIPA511830 Supplier Invitrogen™ Supplier No. PA511830
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine based on sequence homology.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen 4EBP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene EIF4EBP1
Gene Accession No. Q13541
Gene Alias 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Gene Symbols EIF4EBP1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 48-77 amino acids from human EIF4EBP1.
Purification Method Protein A, Antigen Affinity chromatography
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1978
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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