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4EBP1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501571548
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50-157-1548 10 μL
50-157-1547 100 μL
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Catalog No. 50-157-1548 Supplier Bethyl Laboratories, Inc Supplier No. IHC00133T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Rabbit, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, hirteen-lined ground squirrel, Chinese

EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Specifications

Antigen 4EBP1
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene EIF4EBP1
Gene Accession No. Q13541, Q60876
Gene Alias 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
Gene Symbols Eif4ebp1
Host Species Rabbit
Immunogen Between 75 and C-term
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13685, 1978
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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