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Alfa Aesar™ 5-Azacytidine, 98%

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Quantity:
1g
5g
320-67-2
C8H12N4O5
244.207
MFCD00006539
NMUSYJAQQFHJEW-KVTDHHQDSA-N
5-azacytidine,azacitidine,ladakamycin,azacytidine,vidaza,mylosar,azacitidina,azacitidinum,5-azacitidine,azacitidinum inn-latin
9444
CHEBI:2038
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
320-67-2
C8H12N4O5
244.207
MFCD00006539
NMUSYJAQQFHJEW-KVTDHHQDSA-N
5-azacytidine,azacitidine,ladakamycin,azacytidine,vidaza,mylosar,azacitidina,azacitidinum,5-azacitidine,azacitidinum inn-latin
9444
CHEBI:2038
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N

Causes DNA demethylation or hemi-demethylation; a powerful mutagen

Applications
5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

Solubility
Soluble in water.

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Color White
Quantity 1g
Melting Point 226°C to 232°C (decomposition)
Beilstein 620461
Merck Index 14,890
Solubility Information Soluble in water.
Formula Weight 244.2
Physical Form Powder
Percent Purity 98%
Chemical Name or Material 5-Azacytidine

GHS H Statement
H340-H350-H302
May cause genetic defects.
May cause cancer.
Harmful if swallowed.

P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c

H302-H340-H350

EINECSNumber : 206-280-2

RTECSNumber : XZ3017500

TSCA : No

Recommended Storage : Store at -20°C