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  6. 5-Carboxylcytosine (5-caC) Polyclonal Antibody, Active Motif™ 

5-Carboxylcytosine (5-caC) Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501994147
Encompass
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100 μL
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50-199-4147 100 μL
50-199-4148 10 μL
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Catalog No. 50-199-4147 Supplier Active Motif Supplier No. 61225
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Description

Rabbit Polyclonal Antibody

5-carboxylcytosine is the final oxidized derivative of 5-methylcytosine, a type of DNA methylation. 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine. These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family. 5-carboxylcytosine has been shown to cause reduced fidelity of RNA Polymerase II. Decreased levels of 5-hydroxymethylcytosine has been found in some cancers.

Specifications

Antigen 5-Carboxylcytosine (5-caC)
Applications Dot Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 30% glycerol and 0.035% sodium azide; pH
Host Species Rabbit
Immunogen This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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