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Invitrogen™ 5-Carboxylcytosine Recombinant Rabbit Monoclonal Antibody (RM462)
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Catalog No. PIMA544548
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50 μg
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Catalog No. Quantity
PIMA544548 50 μg
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Catalog No. PIMA544548 Supplier Invitrogen™ Supplier No. MA544548
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody reacts to human NeuN (Fox3, RBFOX3). The clone may also react to mouse or rat NeuN, as predicted by immunogen homology.

5-carboxylcytosine is the final oxidized derivative of 5-methylcytosine, a type of DNA methylation. 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine. These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family. 5-carboxylcytosine has been shown to cause reduced fidelity of RNA Polymerase II. Decreased levels of 5-hydroxymethylcytosine has been found in some cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen 5-Carboxylcytosine
Applications Dot Blot, ELISA
Classification Recombinant Monoclonal
Clone RM462
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Host Species Rabbit
Immunogen KLH-conjugated 5-Carboxylcytosine.
Purification Method Protein A
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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