5-Formylcytosine (5-fC) Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Supplier:  Active Motif 61227

Catalog No. 50-199-3248

Description

5-formylcytosine is an oxidized derivative of 5-methylcytosine, a type of DNA methylation. 5-formylcytosine is a nucleobase analogue with a cytosine that possesses a hydrogen at position 5 that has been replaced by a formyl group. 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine. These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family. 5-formylcytosine has been shown to determine nucleosome organization and plays a role in regulating transcription.

Specifications

• Antigen: 5-Formylcytosine (5-fC)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Target Molecule: Chemical

• Applications: Dot Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Immunogen: This 5-Formylcytosine antibody was raised against 5-formylcytidine conjugated to kLH and recognizes 5-formylcytosine.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Product Type: Antibody
• Isotype: IgG