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5-Formylcytosine (5-fC) Rabbit anti-Chemical, Unconjugated, Polyclonal, Active Motif™
SDP

Catalog No. 501994145
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10 μL
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Catalog No. Quantity
50-199-4145 10 μL
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Catalog No. 50-199-4145 Supplier Active Motif Supplier No. 61223
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Description

Rabbit Polyclonal Antibody

5-formylcytosine is an oxidized derivative of 5-methylcytosine, a type of DNA methylation. 5-formylcytosine is a nucleobase analogue with a cytosine that possesses a hydrogen at position 5 that has been replaced by a formyl group. 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine. These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family. 5-formylcytosine has been shown to determine nucleosome organization and plays a role in regulating transcription.

Specifications

Antigen 5-Formylcytosine (5-fC)
Applications Dot Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 30% glycerol and 0.035% sodium azide; pH
Host Species Rabbit
Immunogen This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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