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  6. 5-methylcytosine Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™ 

5-methylcytosine Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™
SDP

Catalog No. 501993732
Encompass
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100 μg
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50-199-3732 10 μg
50-199-3731 100 μg
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Catalog No. 50-199-3732 Supplier Active Motif Supplier No. 91188
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Description

Mouse Recombinant Monoclonal Antibody

Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.

Specifications

Antigen 5-methylcytosine
Applications Dot Blot
Classification Monoclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias 5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Host Species Mouse
Immunogen This antibody was raised against 5-methylcytosine conjugated to kLH.
Purification Method Protein A
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
Target Molecule Chemical
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