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Invitrogen™ 5-Methylcytosine Recombinant Rabbit Monoclonal Antibody (10S5V10)
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Catalog No. PIMA542759
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100 μL
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PIMA542759 100 μL
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Catalog No. PIMA542759 Supplier Invitrogen™ Supplier No. MA542759
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Description

Rabbit Recombinant Monoclonal Antibody

5-Methylcytosine Recombinant Monoclonal Antibody for ELISA, DB

Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
TRUSTED_SUSTAINABILITY

Specifications

Antigen 5-Methylcytosine
Applications Dot Blot, ELISA
Classification Recombinant Monoclonal
Clone 10S5V10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Alias 5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3
Host Species Rabbit
Immunogen 5mC conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical, Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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