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Tocris Bioscience™ 5-Ph-IAA-AM
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Catalog No. 789350
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78-935-0 50 mg
78-931-0 10 mg
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Catalog No. 78-935-0 Supplier Tocris Bioscience™ Supplier No. 7893/50
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Description

Selective and potent TAG Degrader for auxin-inducible degron 2 system; 5-Ph-IAA analog

5-Ph-IAA-AM is a potent and selective "Bump & Hole" TAG Degrader, for use within an auxin-inducible degron (AID2) system; it is an egg-permeant analog of 5-Ph-IAA (Cat. No. 7392). 5-Ph-IAA-AM induces selective degradation of a target protein tagged with a single-point mutant AtTIR1F79G F-box protein. 5-Ph-IAA-AM induces target protein degradation in C. elegans embryos. No developmental abnormality is observed when the embryos are treated with 50 μM 5-Ph-IAA-AM.

Specifications

Chemical Name or Material Acetoxymethyl 2-(5-phenyl-1H-indol-3-yl)acetate
Quantity 50 mg
Target TAG Degradation Platforms
Molecular Formula C19H17NO4
Purity 0.98
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