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Invitrogen™ 53BP2 Polyclonal Antibody
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Catalog No. PIPA5105248
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100 μL
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PIPA5105248 100 μL
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Catalog No. PIPA5105248 Supplier Invitrogen™ Supplier No. PA5105248
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ASPP2.

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
TRUSTED_SUSTAINABILITY

Specifications

Antigen 53BP2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TP53BP2
Gene Accession No. Q13625
Gene Alias 53BP2; Apoptosis-stimulating of p53 protein 2; apoptosis-stimulating protein of p53, 2; ASPP2; BBP; Bcl2-binding protein; P PPP1R13A; P53BP2; PPP1R13A; Renal carcinoma antigen NY-REN-51; TP53BP2; transformation related protein 53 binding protein 2; Trp53bp2; tumor protein p53 binding protein 2; tumor protein p53 binding protein, 2; tumor suppressor p53-binding protein 2
Gene Symbols TP53BP2
Host Species Rabbit
Immunogen A synthesized peptide derived from human TP53BP2(Accession Q13625), corresponding to amino acid residues G672-R722.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 305025, 7159
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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