Invitrogen™ 5T4 Monoclonal Antibody (524731)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524228

Catalog No. PIMA524228

Description

In direct ELISAs, 100% cross-reactivity with recombinant mouse 5T4 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009].

Specifications

• Antigen: 5T4
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q13641
• Gene Symbols: TPBG
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human 5T4 Ser31-Ser355.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: 524731
• Conjugate: Unconjugated
• Gene: TPBG
• Gene Alias: 5T4; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4AG; 5T4-AG; AW495680; M6P1; TPBG; Trophoblast glycoprotein; WAIF1; Wnt-activated inhibitory factor 1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 7162
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized