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Tocris Bioscience™ 7rh

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Quantity:
5 mg
Description
7rh is a potent and selective DDR1 inhibitor (IC50 = 6.8 nM). Exhibits selectivity for DDR1 over DDR2, Bcr-Abl and c-Kit (IC50 values are 101.4 and 355 nM and > 10 μM, respectively) and a range of other kinases. Inhibits proliferation of cancer cell lines expressing high levels of DDR1 in vitro and suppresses cancer cell invasion, adhesion and tumorigenicity. Orally bioavailable.
Specifications
Specifications
Chemical Name or Material | 4-Ethyl-N-[3-[(4-methyl-1-piperazinyl)methyl]-5-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)benzamide |
CAS | 1429617-90-2 |
Quantity | 5 mg |
Molecular Formula | C30H29F3N6O |
Purity | 98% |
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