9-beta-D-Arabinofuranosyladenine, 99%

Description

CAS: 5536-17-4 | C10H13N5O4 | 267.25 g/mol

Vidarabine is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine is an inhibitor of A cyclase and DNA Polymerase. Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling. Cell-permeable adenylate cyclase inhibitor; in detergent-dispersed rat brain preparation, IC50 = 30 ?M. Clinically significant antiviral agent, especially against herpes simplex (HSV),1 by inhibition of DNA polymerase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Vidarabine is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine is an inhibitor of A cyclase and DNA Polymerase. Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling. Cell-permeable adenylate cyclase inhibitor; in detergent-dispersed rat brain preparation, IC50 = 30 μM. Clinically significant antiviral agent, especially against herpes simplex (HSV),1 by inhibition of DNA polymerase.

Solubility
Soluble in DMF (10 mg/ml), 0.5 M HCl (50 mg/ml), DMSO (53 mg/ml at 25°C), ethanol (<1mg/mL at 25°C), and water (3 mg/ml at 25°C).

Notes
Keep container tightly closed. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 5536-17-4
• Molecular Formula: C10H13N5O4
• Molecular Weight (g/mol): 267.25
• MDL Number: MFCD00065471,MFCD00065471,MFCD00475667,MFCD00005752,MFCD00065471
• InChI Key: OIRDTQYFTABQOQ-UHFFFAOYNA-N
• Synonym: 3s,4r,5r-2-6-aminopurin-9-yl-5-hydroxymethyl oxolane-3,4-diol, prestwick_983, 9-lyxofuranosyladenine
• PubChem CID: 6420052
• IUPAC Name: (3S,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• SMILES: NC1=C2N=CN(C3OC(CO)C(O)C3O)C2=NC=N1

• Color: White
• Quantity: 25 g
• Beilstein: 624881
• Merck Index: 14,9976
• Solubility Information: Soluble in DMF (10mg/ml),0.5 M HCl (50mg/ml),DMSO (53mg/ml at 25°C),ethanol (<1mg/ml at 25°C),and water (3mg/ml at 25°C).
• Formula Weight: 267.24
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: 9-beta-D-Arabinofuranosyladenine

Safety and Handling

Hazard Category	H361
Hazard Statement	GHS H Statement H361 Suspected of damaging fertility or the unborn child.
Precautionary Statement	P201-P202-P281-P308+P313-P501c
EINECSNumber	226-893-9
RTECSNumber	AU6200000
TSCA	Yes
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only