Invitrogen™ 90K/Mac-2BP Monoclonal Antibody (SP-2), FITC, eBioscience™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ BMS146FI

Catalog No. 50-178-06

Description

Description: BMS146 specifically recognizes Mac-2 (galectin-3) mucin-like binding domain of human 90K/Mac-2BP. Mac-2BP is a highly glycosylated protein that plays a major role in cancer research. Elevated levels in sera have been found in many patients suffering from various types of cancer or viral infections. Purity: >95%. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

Specifications

• Antigen: 90K/Mac-2BP
• Classification: Monoclonal
• Concentration: 10 μL/Test
• Formulation: TBS with 1% BSA and 0.02% sodium azide; pH 7.2-7.4
• Gene Accession No.: Q08380
• Gene Symbols: LGALS3BP
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3959
• Content And Storage: 4°C, store in dark
• Form: Liquid

• Applications: Flow Cytometry
• Clone: SP-2
• Conjugate: FITC
• Gene: LGALS3BP
• Gene Alias: 90K; basement membrane autoantigen p105; BTBD17B; CyCAP; Cyp-C-associated protein; galectin 3 binding protein; galectin-3-binding protein; gp90; L3 antigen; Lectin; lectin galactoside-binding soluble 3 binding protein; lectin galactoside-binding soluble 3-binding protein; lectin, galactoside binding soluble 3 binding protein; lectin, galactoside-binding, soluble, 3 binding protein; Lgals3bp; M2BP; mac-2 BP; mac-2-binding protein; MAC2BP; MAC-2BP; MAC-2-BP; mama; peptidylprolyl isomerase C-associated protein; Ppicap; Protein 90K; Protein MAMA; serum protein 90K; similar to Galectin-3 binding protein precursor (Lectin galactoside-binding soluble 3 binding protein) (Mac-2 binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K); TANGO10B; transport and golgi organization 10 homolog B; tumor-associated antigen 90K
• Host Species: Mouse
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1